Lyophilization

Aseptic Lyophilization Capabilities at JHS

We offer a range of cutting-edge lyophilizers that includes both GEA and BOC Edwards units. These machines provide high-speed commercial lyophilization and accommodate products that require loading onto pre-frozen shelves at temperatures as low as -45°C.

We prioritize efficiency and reliability when it comes to your project. We fulfill these goals using automated shelf loading and unloading, along with clean in place (CIP) and steam in place (SIP) systems. Additionally, our custom-designed low humidity and low-temperature vial loading area ensures optimal product quality.

Facility Capabilities

Our Clinical Trial Area lyophilizer is equipped with CIP and SIP precise cold shelf loading at -45°C and room dehumidification. We maintain product integrity throughout the lyophilization process.

Our facility can handle vial sizes ranging from small to large, providing versatility for various applications. Rest assured, our protected and isolated RAID 5 PC guarantees increased data reliability and performance.

Commercial Lyophilization

JHS can handle your lyophilization projects: from clinical to commercial sized batches.

Automated CIP, SIP, and Vial (un)loading
Process up to 165 vials/minute
-45°C cold shelf loading

Lyo Capacity

Currently, JHS has 8 lyophilizers ready for production-use, with another available in 2025. In 2026, two additional lyophilizers will be qualified as part of our ongoing expansion project.

Shelf Space	Vial Size	Batch Size
115 - 400 ft²	2 mL - 100 mL	Up to 153,000

Clinical Trial Lyophilization

Freeze-dry your clinical trial project with our clinical trial lyophilizer, specifically suited for small lots.

Automated CIP, SIP, and Vial (un)loading
External condenser
-45°C cold shelf loading

Shelf Space	Vial Size	Batch Size
30 ft²	Up to 5 mL	Up to 4,500

Stay Up to Date with JHS

Case Study: Expediting Cold Chain Supply Resources

A COVID-19 therapeutic product required a very large quantity of compounding materials to be stored under refrigerated conditions. The need was far greater than JHS’ existing capacity for cold storage given the scale of the pandemic.

Case Study: Adapting Equipment to Keep Pace with Demand

JHS applied innovative thinking. They rapidly identified alternatives, such as previously owned equipment that could adapt and qualify for manufacturing. JHS project managers and the tech transfer team also designed alternative solutions.

Ocugen Secures Manufacturing Partnership for US Production of COVID-19 Vaccine Candidate, COVAXIN®

Ocugen, Inc. a biopharmaceutical company focused on discovering, developing, and commercializing gene therapies to cure blindness diseases and developing a vaccine to save lives from COVID-19, announced that it has entered into an agreement with Jubilant HollisterStier of Spokane, Washington for manufacturing of vaccine candidate COVAXIN® for the US and Canadian markets.

Lyophilization

Aseptic Lyophilization Capabilities at JHS

Facility Capabilities

Commercial Lyophilization

Lyo Capacity

Clinical Trial Lyophilization

Stay Up to Date with JHS

Case Study: Expediting Cold Chain Supply Resources

Case Study: Adapting Equipment to Keep Pace with Demand

Ocugen Secures Manufacturing Partnership for US Production of COVID-19 Vaccine Candidate, COVAXIN®

Begin the Manufacturing Process Now