Joshua Brown Poster

Smarter Classification: Leveraging CCI Testing to Reduce Defect Criticality for Lyophilized Products

Smarter Classification: Leveraging CCI Testing to Reduce Defect Criticality for Lyophilized Products

 

Explore how JHS experts leverage data from CCI (Container Closure Integrity) testing to refine defect classification, improve inspection accuracy, and minimize unnecessary batch discards and rework.

Read this poster to learn about

  • The impact of CCI testing on PBNS defect assessment
  • The relationship between defect classification and radiochemical purity (RCP) outcomes
  • How JHS achieved a greater than 50% reduction in rework for AQL failures and increased Right First Time (RFT) batches

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Joshua Brown
Joshua Brown, Manager of Secondary Manufacturing at JHS
Originally Presented at: PDA Visual Inspection Forum 2026 in Dublin, Ireland